Jeff Sessions, MD.

[Darth]

Jeff Sessions' Advice to Pain Patients: 'Take Some Aspirin' and 'Tough It Out'

This is exactly where the woo of alternative medicine, Big Pharma is bad m'kay, gets us:


First his ridiculous stance on marijuana, now this gem.

It's cool, he even pulls the "You wouldn't understand, you weren't a Marine" line in this one too! Buy is that getting old.

 

[holdover]

He is nobody to make any kind of medical recommendations. .But His point was clear to me. Stop being a fucking crybaby and asking for drugs for things that don't require drugs . People are taking drugs for pimples on their ass .Its a joke.

As AG, He was addressing an opioid problem in the US which is real . I agree, he was out of line to make a comment on medical advice .

 

[holdover]

Your ignorance of how things work in the business world is shocking . Big pharma is big business. You really think they spend billions of dollars in advertising to help people? Or to sell them something? If people are healthy , they lose profits ,as a business model its unsustainable. Big pharma is profit driven not health driven.


Highly publicized cases of fabrication or falsification of data in clinical trials have occurred in recent years and it is likely that there are additional undetected or unreported cases. We review the available evidence on the incidence of data fraud in clinical trials, describe several prominent cases, present information on motivation and contributing factors and discuss cost-effective ways of early detection of data fraud as part of routine central statistical monitoring of data quality. Adoption of these clinical trial monitoring procedures can identify potential data fraud not detected by conventional on-site monitoring and can improve overall data quality.

Keywords: central statistical monitoring, data fabrication and falsification, data fraud, data quality
Honesty and truthfulness are bedrock principles of scientific research. Adherence to these principles is essential both for the progress of science and the public perception of scientific results [1–3]. Deviations from these principles may generally be considered scientific misconduct or fraud, although the US Public Health Service defines research misconduct more narrowly, restricting it to the most egregious practices [4]:

• “Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results;
• Fabrication is making up data or results and recording or reporting them;
• Falsification is manipulating research materials, equipment, or processes, or changing or omitting data or results such that the research is not accurately represented in the research record;
• Plagiarism is the appropriation of another person’s ideas, processes, results, or words without giving appropriate credit;
• Research misconduct does not include honest error or differences of opinion.”

Modern examples of scientific fraud are provided in recent papers by Stroebe et al. [29], who list a sample of 40 notorious cases and by Sovocool [30], who provides a table of 11 examples of high profile cases. The US Office of Research Integrity, the office charged with investigations of research misconduct by grant supported investigators, provides on-line summaries of the results of their investigations, including the penalties for those found to have committed fraud [31]. There is even a blog (Retraction Watch) listing and discussing retractions of peer-reviewed scientific papers, many of which are the result of scientific misconduct [32]. More than 2000 scientific articles have been retracted over the last 40 years, many in the biomedical sciences. Nine authors have more than 20 retractions apiece [33]. The number of retractions has increased dramatically in recent years and most of these retractions are due to research misconduct, especially data fraud [34]. A brief account of several prominent cases of data fraud in clinical trials illustrates the issues raised by such misconduct.


Roger Poisson
In 1994 it was reported by the leaders of the National Surgical Adjuvant Breast and Bowel Project (NSABP) that a NSABP clinical investigator, Dr. Roger Poisson of St. Luc Hospital in Montréal, Canada had committed scientific fraud by fabrication or falsification of data on several NSABP breast cancer trials from 1977 through 1990 [35,36]

Robert Fiddes
In the 1990’s Dr. Robert Fiddes was the director of the Southern California Research Institute, a for-profit institution, and was the lead clinical investigator for a large number of clinical trials conducted for pharmaceutical company sponsors. Dr. Fiddes was well-known as an investigator who could recruit patients rapidly to clinical trials with a low drop-out rate. Unfortunately, to maintain his highly successful business Dr. Fiddes had been conducting scientific fraud on an impressive scale for over a decade


Harry W Snyder Jr & Renee Peugot
In 1994, Dr. Harry W Snyder Jr, a prominent dermatologist and scientist at BioCryst Pharmaceuticals, a biotech company founded in 1986 in Birmingham, Alabama, was overseeing a clinical trial sponsored by BioCryst at the University of Alabama at Birmingham (UAB), where his wife, Renee Peugot, a registered nurse at the University, was the study coordinator responsible for the day-to-day conduct of the trial. Both had considerable financial interests in BioCryst and a vested interest in the outcome of the trial.............. Felony convictions followed for both Snyder and Peugot, with prison sentences of 3 years and 2.5 years respectively, payment of financial restitution and permanent debarment by the FDA. The University also had all clinical trials stopped for a period of time while the investigation was underway for failure to properly oversee the trials. [42,43]


Data fraud in clinical trials


A New Name and Package for Prozac for Treating Severe PMS Symptoms

Arriving in pharmacies today is Prozac--newly repackaged and re-marketed under the name Sarafem--but with the identical formula as Prozac.

Sarafem has been approved by the US Food and Drug Administration (FDA) for a relatively-new classification of mental disorder called PMDD, which is an extreme form of PMS suffered by 3% to 5% of women who experience PMS symptoms

 

[Darth]

Your ignorance of how things work in the business world is shocking . Big pharma is big business. You really think they spend billions of dollars in advertising to help people? Or to sell them something? If people are healthy , they lose profits ,as a business model its unsustainable. Big pharma is profit driven not health driven.


Highly publicized cases of fabrication or falsification of data in clinical trials have occurred in recent years and it is likely that there are additional undetected or unreported cases. We review the available evidence on the incidence of data fraud in clinical trials, describe several prominent cases, present information on motivation and contributing factors and discuss cost-effective ways of early detection of data fraud as part of routine central statistical monitoring of data quality. Adoption of these clinical trial monitoring procedures can identify potential data fraud not detected by conventional on-site monitoring and can improve overall data quality.

Keywords: central statistical monitoring, data fabrication and falsification, data fraud, data quality
Honesty and truthfulness are bedrock principles of scientific research. Adherence to these principles is essential both for the progress of science and the public perception of scientific results [1–3]. Deviations from these principles may generally be considered scientific misconduct or fraud, although the US Public Health Service defines research misconduct more narrowly, restricting it to the most egregious practices [4]:

• “Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results;
• Fabrication is making up data or results and recording or reporting them;
• Falsification is manipulating research materials, equipment, or processes, or changing or omitting data or results such that the research is not accurately represented in the research record;
• Plagiarism is the appropriation of another person’s ideas, processes, results, or words without giving appropriate credit;
• Research misconduct does not include honest error or differences of opinion.”

Modern examples of scientific fraud are provided in recent papers by Stroebe et al. [29], who list a sample of 40 notorious cases and by Sovocool [30], who provides a table of 11 examples of high profile cases. The US Office of Research Integrity, the office charged with investigations of research misconduct by grant supported investigators, provides on-line summaries of the results of their investigations, including the penalties for those found to have committed fraud [31]. There is even a blog (Retraction Watch) listing and discussing retractions of peer-reviewed scientific papers, many of which are the result of scientific misconduct [32]. More than 2000 scientific articles have been retracted over the last 40 years, many in the biomedical sciences. Nine authors have more than 20 retractions apiece [33]. The number of retractions has increased dramatically in recent years and most of these retractions are due to research misconduct, especially data fraud [34]. A brief account of several prominent cases of data fraud in clinical trials illustrates the issues raised by such misconduct.


Roger Poisson
In 1994 it was reported by the leaders of the National Surgical Adjuvant Breast and Bowel Project (NSABP) that a NSABP clinical investigator, Dr. Roger Poisson of St. Luc Hospital in Montréal, Canada had committed scientific fraud by fabrication or falsification of data on several NSABP breast cancer trials from 1977 through 1990 [35,36]

Robert Fiddes
In the 1990’s Dr. Robert Fiddes was the director of the Southern California Research Institute, a for-profit institution, and was the lead clinical investigator for a large number of clinical trials conducted for pharmaceutical company sponsors. Dr. Fiddes was well-known as an investigator who could recruit patients rapidly to clinical trials with a low drop-out rate. Unfortunately, to maintain his highly successful business Dr. Fiddes had been conducting scientific fraud on an impressive scale for over a decade


Harry W Snyder Jr & Renee Peugot
In 1994, Dr. Harry W Snyder Jr, a prominent dermatologist and scientist at BioCryst Pharmaceuticals, a biotech company founded in 1986 in Birmingham, Alabama, was overseeing a clinical trial sponsored by BioCryst at the University of Alabama at Birmingham (UAB), where his wife, Renee Peugot, a registered nurse at the University, was the study coordinator responsible for the day-to-day conduct of the trial. Both had considerable financial interests in BioCryst and a vested interest in the outcome of the trial.............. Felony convictions followed for both Snyder and Peugot, with prison sentences of 3 years and 2.5 years respectively, payment of financial restitution and permanent debarment by the FDA. The University also had all clinical trials stopped for a period of time while the investigation was underway for failure to properly oversee the trials. [42,43]


Data fraud in clinical trials

Yeah, there is a whole thread in the Clubhouse on that one. There is enough BS about Big Phatma for the whole forum in that thread.

"Sick people lose them profits." Don't buy it. People dead from easily preventable diseases that Big Pharma has eradicated don't tend to raise profits.

 

[Darth]

He is nobody to make any kind of medical recommendations. .But His point was clear to me. Stop being a fucking crybaby and asking for drugs for things that don't require drugs . People are taking drugs for pimples on their ass .Its a joke.

As AG, He was addressing an opioid problem in the US which is real . I agree, he was out of line to make a comment on medical advice .

And people are also killing themselves for lack of needed painkillers.

Buck up and get over it buddy doesn't do much for chronic pain sufferers.

Is he on the dole for DARE or something? He's all for expanding the worthless war on drugs.

Even if you are on the side of "big pharma is just in it for the money (which is a good thing btw, profit drives innovation), you know a more "natural" cure many seek to take the edge off? Pot. Well, he hates that too, so his archaic feelings on this trumps the quality of life of millions.

Another Republican that loves victimless crimes and big government when it suits them.

 

[Jezman]

Big Pharmaceutical puts out commercials on TV as any business does. The problem is people believe the misinformation and believe what is being told. When people realize a TV commercial is not a legitimate form of truth, most will fare much better in life. Example how many people believe Milk does you good? Cow's Milk is for cows babies. That is a scientific fact not some made up shit. But 90% of people will fight drinking cows milk is good while it slowly break's down your body.

 

[togmaster]

Today everyone need to blame someone. Sessions is right on this one. If you have to take pain medication know what you are doing and know the consequences. If not just tough it out.

 

[Criticalt]

And people are also killing themselves for lack of needed painkillers.

Buck up and get over it buddy doesn't do much for chronic pain sufferers.

Is he on the dole for DARE or something? He's all for expanding the worthless war on drugs.

Even if you are on the side of "big pharma is just in it for the money (which is a good thing btw, profit drives innovation), you know a more "natural" cure many seek to take the edge off? Pot. Well, he hates that too, so his archaic feelings on this trumps the quality of life of millions.

Another Republican that loves victimless crimes and big government when it suits them.

More and more studies are proving that NSAIDs are better at pain relief than opiods.
So, a doctor gives a long time opiod patient 800mg Ibuprofen. The pain goes away, but the hunger for the opiod does not. The patient says the Ibuprofen doesnt work and demands opiods.
Most pain is caused by inflammation. Opiods limit the pain by relieving pain receptors, masking the pain, but the damaging inflammation is still there.
NSAIDs calms the inflammation, which relieves the pain and relieves the damaging inflammation.
So, the logical next step is to move towards NSAIDs and away from long term opiods.
However, people addicted to opiods are a tough crowd to convert.

 

[holdover]

Because back room deals , bribes, unscrupulous behavior , corruption, cheating, lying, doesn't happen in the medical or scientific fields .What a laugh. Law suits are baked into the cake , They already know that if 15 % of the people get sick , 3 or 5 % may be able to prove it was their pills , if those lawsuits add up to 150 million dollars they know they need to make 300 million to make a decent profit before pulling the plug on it. So they price it accordingly.

 

[holdover]

"Sick people lose them profits." Don't buy it. People dead from easily preventable diseases that Big Pharma has eradicated don't tend to raise profits.


LOL , Sometimes you really shock me. Your a total sheep when it comes to thinking for yourself.

Look , If Eli Lilly found a pill to cure cancer . Do you think it would be in their best interests to release it? every single oncologist in the country would be out of business overnight , every single cancer institute would be out of business the next day . where is a cancer doctor who spent his life studying and treating the disease going to work? he has to go back to school now? all their equipment used for fighting cancer is useless . every cancer medicine in the world would be outdated and useless, No more chemo, no more bone marrow transplants.

Sick people are good for business, its their main customers! you want to get rid of them? A little common sense is needed here , There is no profit in the cure, the money is in the treatment . repeated treatment over a lifetime. That's where the money is .

 

[Darth]

"Sick people lose them profits." Don't buy it. People dead from easily preventable diseases that Big Pharma has eradicated don't tend to raise profits.


LOL , Sometimes you really shock me. Your a total sheep when it comes to thinking for yourself.

Look , If Eli Lilly found a pill to cure cancer . Do you think it would be in their best interests to release it? every single oncologist in the country would be out of business overnight , every single cancer institute would be out of business the next day . where is a cancer doctor who spent his life studying and treating the disease going to work? he has to go back to school now? all their equipment used for fighting cancer is useless . every cancer medicine in the world would be outdated and useless, No more chemo, no more bone marrow transplants.

Sick people are good for business, its their main customers! you want to get rid of them? A little common sense is needed here , There is no profit in the cure, the money is in the treatment . repeated treatment over a lifetime. That's where the money is .

There is no money in the cure.

Right.

If you had cancer, and I had a pill you could take to save your life, you wouldn't pay any amount of money possible for it? Flawless logic.

10 Reasons Why Hidden Cancer Cure Conspiracy Theories Fail.

 

[Darth]

More and more studies are proving that NSAIDs are better at pain relief than opiods.
So, a doctor gives a long time opiod patient 800mg Ibuprofen. The pain goes away, but the hunger for the opiod does not. The patient says the Ibuprofen doesnt work and demands opiods.
Most pain is caused by inflammation. Opiods limit the pain by relieving pain receptors, masking the pain, but the damaging inflammation is still there.
NSAIDs calms the inflammation, which relieves the pain and relieves the damaging inflammation.
So, the logical next step is to move towards NSAIDs and away from long term opiods.
However, people addicted to opiods are a tough crowd to convert.

When these patients decide, on their own, to pursue other options, and our government doesn't step in and drive them to kill themselves because of the pain, I'll care about the merits of NSAIDs and Sessions theories on them.

 

[holdover]

There is no money in the cure.

Right.

If you had cancer, and I had a pill you could take to save your life, you wouldn't pay any amount of money possible for it? Flawless logic.

10 Reasons Why Hidden Cancer Cure Conspiracy Theories Fail.

Economics darth , learn it. How much money would it cost? vs how much money they would lose? They would loses trillions in one year , where are they going to make up the difference? Charge a million dollars a pill? LOL I couldn't afford it. and they couldnt sell them at that price . Its a loser .

 

[Darth]

All addressed in that article, which of course you didn't read.

 

[holdover]

Of course.

 

[Jezman]

A business making money does not change there model till it becomes no longer profitable!

 

[SmallGameAddict]

I think President Trump said it best during his campaign..."Follow the Money".

 

[Robin]

One mans medicine is another mans poison. Stay the fuck out of my medicine cabinet JEFFY!!! You got a got a target rich environment filled with Rino's and Jackasses and your mouse hunting, wake the fuck up Jeffy, WAKE UP!!!! HEY!!!!
Robin

 

[Criticalt]

When these patients decide, on their own, to pursue other options, and our government doesn't step in and drive them to kill themselves because of the pain, I'll care about the merits of NSAIDs and Sessions theories on them.

Thats the problem, patients cannot decide for themselves, or wont decide for themselves.
Opiate addiction is horrifying and almost impossible to kick on your own.
The immense self control and will power to detox and withdraw is very difficult. Add to that a doctor that over prescribes and is just a phone call away, makes it almost insurmountable.
This IS the epidemic, long time pain sufferers becoming so addicted and dependent they see no way out.
The average recreational opiate addict usually cleans up after a short time due to difficulty getting opiates.
The problem is doctors prescribing opiates long after the need for pain control because the patient NEEDS them.
Another problem is, where are the recreational opiates comming from?.
Answer.....opiate patients who sell their drugs for cash.
How can they sell them if they are on the verge of suicide because of pain?
Answer......they are not in pain, they have "soft" doctors that prescribe large quantities of opiates to make money.
Opiates cause FAR more damage than they do good.
Starting a patient on pain management correctly is the answer.
Most pain management doctors these days use opiates very, very sparingly for very short periods of time.
Treating the cause of pain is far more effective than covering the pain.
This is a topic I am very close to.
My mom is a long time pain sufferer who has successfully transitioned away from opiates for pain.
Also, where I cime from this is a huge problem.
I have numerous friends and acquaintances that are, or have been horribly effected by opiates.
A good friend of mine is on deaths door right now because of 15 years of doctor prescibed opiates for a back injury.
Due to his heavy use, he now has gastroparesis, aka stomach paralysis.
He cannot hold any food down and cannot pass waste. He has lost 60 pounds in 6 months.
His prognosis is still not known.
He is a single father of 2 girls.

 

[Criticalt]

I will add that Ive been a huge detractor of Sessions from day one.
I believe he is an incompetent weakling.
I didnt even read the article and dont know alot about big pharm.
What I do know about is the opiate epidemic and overuse, and safer alternatives.
Unfortunately its been a big part of my life.

 

[GuyMontag]

I can't remember a single Attorney General in my lifetime who wasn't either a total political tool, fool, or combination of the two. Meese, Reno, Holder....Sessions is just another joker who's parlayed his political support into a job he's not remotely capable of performing.

 

[Dr. Evil]

Where ever you stand regarding Session's comments, based on other threads, I'm hoping the irony of one individual not an MD/healthcare provider criticizing another individual for his opinions due to him also not being an MD/healthcare provider isn't just lost on me.

 

[holdover]

Im no fan of sessions either. I think he should be thrown out .

In my opinion the gist of what the was saying is that opioids are overprescribed , and people demand medication for yellow toenails. and brittle hair.

Health doesn't come in bottle.

 

[Darth]

Oh it's got nothing to do with wether he's a doctor or not. It does have to do with his demonstrably wrong position.

If you are going to pretend to be a Dr, like the Evil one does here on a daily basis, at least make sure your facts are straight. Being totally wrong seems to be a common theme amongst these holiday inn express doctors.

 

[Darth]

Im no fan of sessions either. I think he should be thrown out .

In my opinion the gist of what the was saying is that opioids are overprescribed , and people demand medication for yellow toenails. and brittle hair.

Health doesn't come in bottle.

But lifesaving pain medications do.

That is unless Jeff has anything to say about it.

 

[Robin]

Oh it's got nothing to do with wether or not he's a doctor or not. It does have to do with his demonstrably wrong position.

If you are going to pretend to be a Dr, like the Evil one does here on a daily basis, at least make sure your facts are straight. Being totally wrong seems to be a common them amongst these holiday inn express doctors.

Its my understanding that the man that goes by Dr. Evil on this forum is a Chiropractor and a Doctor of that particular medical field. What is your effing problem?
Robin

 

[Darth]

Its my understanding that the man that goes by Dr. Evil on this forum is a Chiropractor and a Doctor of that particular medical field. What is your effing problem?
Robin

He's not a medical doctor, yet peddles his bullshit and, when confronted with information that debunks his snake oil woo, claims "but I'm a doctor, and therefore qualified to give advice."

Doesn't understand the difference between ethyl and methyl mercury, or that water is a chemical, but tries to paint others as not knowing what they are taking about, while spreading misinformation that gets people killed.

That's my effing problem.

 

[Dr. Evil]

Its my understanding that the man that goes by Dr. Evil on this forum is a Chiropractor and a Doctor of that particular medical field. What is your effing problem?
Robin

You are correct @Robin. Doctor of Chiropractic. 5 year program done in 3.5 years plus a BS in my undergraduate. Di section, CNS, PNS, histology, nutrition, x-ray analysis and differential diagnosis, etc.. Chiropractic Curriculum Organization and Design for Life University Also, 3 years of study regarding functional medicine and bio-energetic testing with nutrition. Some would say not a "real" doctor lol. I say if being a "real" doctor means doing surgery and prescribing drugs then yes, I am happily not a "real" doctor. BTW, can only imagine what that ignorant asshole had to say about me.

 

[Robin]

He's not a medical doctor, yet peddles his bullshit and, when confronted with information that debunks his snake oil woo, claims "but I'm a doctor, and therefore qualified to give advice."

Doesn't understand the difference between ethyl and methyl mercury, or that water is a chemical, but tries to paint others as not knowing what they are taking about, while spreading misinformation that gets people killed.

That's my effing problem.

It is a different medical philosophy, it is not wrong, just different and many many people have been helped by it. I don't think even a medical doctor as you call them would argue with the good things that can be achieved through Chiropractics and practices that are ancillary to it. I go to a medical doctor when I need help but recognize the benefits of many medical philosophies.
I don't think that is your effing problem, just a symptom.
Robin

 

[Darth]

It is a different medical philosophy, it is not wrong, just different and many many people have been helped by it. I don't think even a medical doctor as you call them would argue with the good things that can be achieved through Chiropractics and practices that are ancillary to it. I go to a medical doctor when I need help but recognize the benefits of many medical philosophies.
I don't think that is your effing problem, just a symptom.
Robin

"It's not wrong, it's just different."

Yes, different in the fact that it doesn't work.

You don't think that Medical Doctors as "the entire scientific community" (not me) calls them strongly question the validity of Chiropractors? Because you're wrong there. No, not "different", wrong. Take a look into the history of the art and see where their skepticism arises.

Another example of something that is wrong, not "diffrient" is this:

https://nygunforum.com/threads/in-g...y-edited-out-non-carcinogenic-findings.17323/

And that's just one of many on here. If being wrong is a "medical philosophy" that is worth a shot, have at it. I just provide the information to those that care.